
Human Biology Was Shaped by the Natural World
For nearly all of human history, we lived in constant contact with the natural world - surrounded by environmental microbes that trained and regulated our immune system.
But in just the last fraction of our human timeline, industrialization, urban living, food processing, and hyper-sanitized environments removed that exposure.
What was once a balanced system is now left without critical inputs — contributing to a more reactive immune state and rising chronic disease.
Deep Coexistence

Industrial Disruption

Technology
Acceleration

Restoring the signals we lost
Kioga is restoring our Old Friends — beneficial, nature-derived microbes that humans co-evolved with for hundreds of thousands of years.
These microbes played a critical role in training the immune system to stay balanced — not overreactive — helping regulate inflammation across the body and brain.
By reintroducing these signals, we are building a new approach to health: one that targets stress, mood, and chronic disease at their biological origin.

Where Immune Balance Meets Brain Function
Introducing NeuroAlly™
Mycolicibacterium petrae KGA-10
NeuroAlly™ is the first ingredient built from the Old Friends category, developed to restore balance across the immune–brain axis at the root of how we experience stress. Developed from a proprietary Old Friends strain, NeuroAlly™ works by recalibrating immune activity, reducing neuroinflammatory tone, and supporting healthy communication between the immune system and the brain. This targets an upstream driver of stress — offering a fundamentally different approach from traditional ingredients.
The High Points

Clinically-Backed Safety and Efficacy
A randomized, placebo-controlled human study demonstrating rapid and meaningful improvements across stress, inflammation, and overall wellbeing.
94% of study participants report significantly reduced stress by Week 2
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84% of study participants report reduced feelings of overwhelm and helplessness in the face of stress by Week 2
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78% of study participants report improvement in emotional wellbeing by Week 8
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