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The root layer of human health

Reuniting humanity with our oldest friends

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Human Biology Was Shaped by the Natural World

For nearly all of human history, we lived in constant contact with the natural world - surrounded by environmental microbes that trained and regulated our immune system.

But in just the last fraction of our human timeline, industrialization, urban living, food processing, and hyper-sanitized environments removed that exposure.

What was once a balanced system is now left without critical inputs — contributing to a more reactive immune state and rising chronic disease.

ERA 1
Deep Coexistence
Homo Sapiens Emerge
Outdoor life, soil, water, animals
Beneficial Microbial Exposure
ERA 2
Industrial Disruption
INDUSTRIAL REVOLUTION BEGINS
Mass urbanization, paved surfaces, move indoors
Beneficial Microbial Exposure
ERA 3
Technology
Acceleration
SCREEN TIME AND REMOTE WORK
Sedentary indoor life, hypersanitization
Beneficial Microbial Exposure
Today

Restoring the signals we lost

Kioga is restoring our Old Friends — beneficial, nature-derived microbes that humans co-evolved with for hundreds of thousands of years.

These microbes played a critical role in training the immune system to stay balanced — not overreactive — helping regulate inflammation across the body and brain.

By reintroducing these signals, we are building a new approach to health: one that targets stress, mood, and chronic disease at their biological origin.

Where Immune Balance Meets Brain Function
Introducing NeuroAlly™

Mycolicibacterium petrae KGA-10

NeuroAlly™ is the first ingredient built from the Old Friends category, developed to restore balance across the immune–brain axis at the root of how we experience stress. Developed from a proprietary Old Friends strain, NeuroAlly™ works by recalibrating immune activity, reducing neuroinflammatory tone, and supporting healthy communication between the immune system and the brain. This targets an upstream driver of stress — offering a fundamentally different approach from traditional ingredients.

The High Points

Targets the root cause at the immune-brain interface, where stress originates
Supports both rapid signaling and long-term immune recalibration
Built for modern formulation with a low-dose, stable profile, and broad application formats
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Clinically-Backed Safety and Efficacy

A randomized, placebo-controlled human study demonstrating rapid and meaningful improvements across stress, inflammation, and overall wellbeing.

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94% of study participants report significantly reduced stress by Week 2

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84% of study participants report reduced feelings of overwhelm and helplessness in the face of stress by Week 2

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78% of study participants report improvement in emotional wellbeing by Week 8

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NeuroAlly™ Fits Where You Are Formulating

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Capsules & tablets

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Powders & stick packs

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Functional beverages

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Bars & snacks

05

Gummies & chews

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Chocolate & confection

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Building Products That Restore What We’ve Lost

NeuroAlly™ gives you access to a new class of ingredients - designed to restore the microbial signals that keep human biology in balance.

Now available for partners building the next generation of stress, mood, and cognitive health products.

Partner With Us